I use all optimized BIOS settings (OoB, no OC yet) despite a few changes listed in detail below:
1.) /AI Tweaker/
a.) ASUS MultiCore Enhancement: Auto
b.) AVX Instruction Core Ratio Negative Offset: "3"
c.) AVX-512 Instruction Core Ratio Negative Offset: "2"
d.) CPU Core Ratio: Sync All Cores
e.) CPU SVID Support: Enabled
f.) DRAM Frequency: DDR4-3200MHz (in my particular case)
2.) /Advanced/CPU Configuration/
a.) Hyper Threading [ALL]: Enabled
b.) MSR Lock Control:Disabled
3.) /Advanced/CPU Configuration/CPU Power Management Configuration/
a.) Enhanced Intel Speed Step Technology (EIST):Enabled
b.) Autonomous Core C-States: Enabled
c.) Enhanced Halt State (C1E):Enabled
d.) CPU C6 report: Enabled
e.) Package C-State: C6(non retention) state
f.) Intel SpeedShift Technology:Enabled
g.) MFC Mode Override: OS Native
4.) /Advanced/Platform Misc Configuration/
a.) PCI Express Native Power Management: Disabled
b.) PCH DMI ASPM: Disabled
d.) ASPM: Disabled
e.) DMI Link ASPM Control: Disabled
f.) PEG - ASMP: Disabled
5.) /Advanced/System Agent Configuration/
a.) Intel VT for Directed I/O (VT-d): Disabled/Enabled
6.) /Boot/
a.) Fast Boot: Disabled
b.) Above 4G Decoding: On
c.) Set your specific Boot Option Priorities
7.) /Boot/Boot Configuration
a.) Boot Logo Display: Auto
b.) Boot up NumLock State: Disabled
c.) Setup Mode: Advanced
8.) /Boot/Compatibility Support Module/
a.) Launch CSM: Disabled